Thermo Fisher Scientific KCNH1 Polyclonal Antibody
Human KCNH1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.6 mg/mL 농도의 액상 형태. 뇌 및 근아세포 발현 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KCNH1 (aa 878–981) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642929 |
Product Specific Information
Immunogen sequence:
DSCDSGITKS DLRLDNVGEA RSPQDRSPIL AEVKHSFYPI PEQTLQATVL EVRHELKEDI KALNAKMTNI EKQLSEILRI LTSRRSSQSP QELFEISRPQ SPES
Antigen sequence identity:
- Mouse: 91%
- Rat: 92%
Target Information
Voltage-gated potassium (Kv) channels are complex ion channels with diverse physiological roles, including regulation of neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
KCNH1 encodes a member of the voltage-gated potassium channel subfamily H, functioning as a pore-forming (alpha) subunit of a non-inactivating delayed rectifier potassium channel.
KCNH1 is activated during myoblast differentiation and is highly expressed in brain and myoblasts. Overexpression may promote cancer cell proliferation.
Alternative splicing results in two transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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