Thermo Fisher Scientific PSMD2 Polyclonal Antibody
PSMD2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. 0.5 mg/mL 액상 형태, TBS 버퍼(0.5% BSA, 0.02% sodium azide) 포함. -20°C 보관.
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- PA518324
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (VILRKNPNYDL) corresponding to the C-terminus amino acids of PSMD2 (aa 898–908). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985766 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha and two rings of seven beta subunits).
- The 19S regulator contains a base (six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal process.
The immunoproteasome plays an essential role in processing class I MHC peptides.
This gene encodes one of the non-ATPase subunits of the 19S regulator lid and may also participate in the TNF signaling pathway via interaction with the TNF type 1 receptor. A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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