Thermo Fisher Scientific CD179b Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD179b for ICC/IF applications. Recombinant immunogen-based antibody purified by antigen affinity chromatography. Provides reliable detection of preB cell receptor component involved in B cell development. For...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CD179b (Recombinant protein control fragment: Product #RP-106324) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2662585 |
Product Specific Information
- Immunogen sequence: GFQSKHNSVTH VFGSGTQLTV LSQPK
- Ortholog identity: Mouse 46%, Rat 50%
Target Information
CD179b (preB cell receptor component) is expressed on proB and preB cells, playing a key role in signal transduction for cellular proliferation and differentiation during B cell development.
It contributes to allelic exclusion at the Ig heavy chain locus and promotes Ig light chain rearrangement.
Mutations can lead to B cell deficiency and agammaglobulinemia, an autosomal recessive disorder characterized by lack of gamma globulins or antibodies.
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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