Thermo Fisher Scientific PTGES2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTGES2, validated for Western blot. Recognizes N-terminal region (aa 200–249). Supplied unconjugated in liquid form, affinity purified, 0.5 mg/mL in PBS with sucrose. Suitable for research use in inflammation ...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PTGES2 (aa 200–249) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577267 |
Product Specific Information
Peptide sequence:
KEVTEFGNKY WLMLNEKEAQ QVYGGKEART EEMKWRQWAD DWLVHLISPN
Sequence homology:
Cow: 79%
Dog: 79%
Human: 100%
Mouse: 86%
Pig: 79%
Rat: 79%
Target Information
The PTGES2 gene encodes prostaglandin E synthase 2 (PTGES2), an enzyme essential for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. It functions downstream of the cyclooxygenase (COX) pathway, interacting with COX-1 and COX-2 enzymes. PTGES2 plays a key role in inflammation, fever generation, and pain by regulating PGE2 levels. This membrane-associated enzyme is distinct from other prostaglandin synthases due to its specific regulatory properties and involvement in immune responses and vascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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