
Thermo Fisher Scientific C12ORF61 Polyclonal Antibody
C12ORF61 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(파라핀 절편)에 사용 가능. Human 시료에 반응하며 Rabbit IgG로 제작됨. 고순도 Protein A 정제 및 안정한 보관용 버퍼로 구성. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human C12ORF61 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chromosome 12 encodes over 1,100 genes within 132 million bases, representing about 4.5% of the human genome. Several skeletal deformities such as hypochondrogenesis, achondrogenesis, and Kniest dysplasia are linked to chromosome 12. Noonan syndrome, associated with heart and facial developmental defects, is caused by a mutant form of the PTPN11 gene product (SH-PTP2). Chromosome 12 also contains a homeobox gene cluster crucial for morphogenesis and a natural killer complex gene cluster encoding C-type lectin proteins that mediate NK cell responses to MHC I interaction. Trisomy 12p results in facial development defects, seizure disorders, and other variable symptoms depending on mosaicism severity. The C12orf61 gene product has been provisionally designated C12orf61 pending further characterization.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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