Thermo Fisher Scientific PINX1 Polyclonal Antibody
Rabbit polyclonal antibody against human PINX1, suitable for WB, IHC, and IP applications. Recognizes residues 225–275 of PIN2 Interacting Protein 1. Supplied as a 1 mg/mL liquid, stored at 4°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225–275 of Human PIN2 Interacting Protein 1 (PINX1, UniProt ID: Q96BK5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. It mediates TRF1 and TERT accumulation in the nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may act as a tumor suppressor by inhibiting cell proliferation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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