Thermo Fisher Scientific HSPA1L Monoclonal Antibody (2-1#)
HSPA1L 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 2-1#). Western blot, IHC, ICC/IF에 사용 가능하며, 단백질 A/G로 정제된 1 mg/mL 액상 형태. 인간 시료에 반응하며, -20°C에서 보관.
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- MA541596
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–30 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2-1# |
| Immunogen | Recombinant Heat Shock 70kDa Protein 1 Like Protein (amino acids 1–641) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899078 |
Target Information
Cells respond to environmental stress by increasing the expression of heat shock proteins (HSPs). The small heat shock proteins, ranging from approximately 15 to >30 kDa, are present in diverse organisms. Elevated expression of certain stress proteins has been linked to neoplasia, as seen in estrogen-induced proteins in breast cancer cells. Hsp27, for example, shows rapid phosphorylation in response to mitogens, tumor promoters, and calcium ionophores. A 24 kDa estrogen-induced protein correlates with steroid hormone receptor expression and is highly expressed in breast carcinoma. Studies also suggest that Hsp27 levels are associated with endometrial adenocarcinomas. Regulation of human Hsp27 by estrogens and heat shock mirrors the control of Drosophila Hsp20 genes by ecdysteroids and heat shock.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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