Thermo Fisher Scientific RACGAP1 Monoclonal Antibody (OTI1C10), TrueMAB
인간 RACGAP1 단백질(아미노산 123-238)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 최적화(1:500–1:2,000). 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼. 세포골격 및 Rac 신호 연구용으로 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific RACGAP1 Monoclonal Antibody (OTI1C10), TrueMAB
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 123–238 of human RACGAP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RAC, a small GTPase in the Ras family, regulates the formation of membrane ruffles, lamellipodia, and filopodia. It is involved in cytoskeletal actin organization and cellular transformation. The p21-activated kinases (PAKs) are direct targets of active Rac and Cdc42, which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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