Thermo Fisher Scientific Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Monoclonal Antibody (KRT20/1991)
Colorectal epithelial marker로 사용되는 Cytokeratin 20 단클론 항체. Western blot 및 IHC에 적합하며, 인간 시료 반응성. Recombinant human KRT20 단백질(aa 196-323)을 면역원으로 사용. Protein A/G 정제, PBS buffer, 보존제 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT20/1991 |
| Immunogen | Recombinant fragment of human KRT20 protein (around aa 196–323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells, specifically expressed in the gastric and intestinal mucosa. Type I cytokeratin genes are clustered in a region of chromosome 17q12–q21.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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