Thermo Fisher Scientific Tankyrase 2 Polyclonal Antibody
Tankyrase 2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 항원 친화 크로마토그래피로 정제된 액상형 항체로, 인간 시료에 반응. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5121562
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- pk
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Thermo Fisher Scientific Tankyrase 2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Ser959–Gly1166 (Accession Q9H2K2), with N-terminal His Tag |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2915134 |
Target Information
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length, and vesicle trafficking (PubMed:11739745, PubMed:11802774, PubMed:19759537, PubMed:21478859, PubMed:23622245, PubMed:25043379).
Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, key components of the beta-catenin destruction complex.
Also mediates poly-ADP-ribosylation of BLZF1, CASC3, and TERF1, contributing to telomere length regulation and proteasome activation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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