Thermo Fisher Scientific CHST1 Polyclonal Antibody
Zebrafish CHST1 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 높은 특이성과 재현성을 제공. Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 341–375 amino acids of DANRE chst1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718518 |
Target Information
Carbohydrate sulfotransferase 1 (CHST1), also referred to as KSGal6ST or KSST, is a keratan sulfate sulfotransferase. It is predominantly expressed in brain and skeletal muscle and localizes to the trans-Golgi network.
CHST1 mediates the sulfation of keratan in the cornea, which is critical for maintaining corneal transparency. It catalyzes the transfer of sulfate groups from 3'-phosphoadenosine 5'-phosphosulfate to position six of internal or terminal galactose residues on growing keratan sulfate chains.
CHST1 also contributes to the generation of L-selectin ligands, and mutations in the CHST1 gene may play a role in macular corneal dystrophy (MCD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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