Thermo Fisher Scientific KIRREL2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KIRREL2 (AAH07312.1, 1 a.a. approximately 219 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KIRREL2,uniProtId:Q6UWL6-1,ncbiNodeId:9606,antigenRange:1-708,antigenLength:708,antigenImageFileName:H00084063-D01P_KIRREL2_Q6UWL6-1_Rabbit.svg,antigenImageFileNamePDP:H00084063-D01P_KIRREL2_Q6UWL6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MLRMRVPALL VLLFCFRGRA GPSPHFLQQP EDLVVLLGEG GAQASLGRRA SASFSEQKNL MRIPGSSDGS SSRGPEEEET GSREDRGPIV HTDHSDLVLE EEGTLETKDP TNGYYKVRGV SVSLSLGEAP GGGLFLPPPS PLGPPGTPTF YDFNPHLGMV PPCRLYRARA GYLTTPHPRA FTSYIKPTSF GPPDLAPGTP PFPYAAFPTP SHPRLQTHV

Target Information

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.