Thermo Fisher Scientific CYP17A1 Monoclonal Antibody (OTI3D9), Biotin, TrueMAB
CYP17A1 단백질을 인식하는 Biotin-conjugated mouse monoclonal antibody. 인간 시료 반응성. Luminex 등 면역분석에 사용 가능. 고순도 친화 크로마토그래피 정제. 연구용으로 스테로이드 생성 경로 연구에 적합.
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Applications
- Luminex (LUM): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D9 |
| Immunogen | Full length human recombinant CYP17A1 protein produced in HEK293T cells |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and has both 17α-hydroxylase and 17,20-lyase activities. It is a key enzyme in the steroidogenic pathway producing progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations are associated with steroid-17α-hydroxylase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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