Thermo Fisher Scientific IFN beta Recombinant Rabbit Monoclonal Antibody (040)
인간 IFN beta에 특이적인 재조합 토끼 단일클론 항체로 높은 특이성과 민감도를 제공합니다. ELISA에 최적화되어 있으며 보존제가 없는 액상 형태입니다. 단기간 4°C, 장기간 -20°C 보관을 권장합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific IFN beta Recombinant Rabbit Monoclonal Antibody (Clone 040)
Applications
- ELISA
Tested Dilution: 1:5,000–1:10,000
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 040 |
| Immunogen | Recombinant Human IFN beta protein (Met1–Asn187) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786362 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
This antibody has specificity for Human IFN beta.
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by natural IFN-producing cells (IPCs) as part of the host immune defense mechanism. IFNs also inhibit tumor development.
IFN-beta binding activates tyrosine kinases Jak1 and Tyk2, leading to phosphorylation of STAT transcription factors and induction of immune response genes. Members of the toll-like receptor (TLR) family also stimulate IFN-beta production.
Clinically, IFN-beta is used for treatment of tumors, infections, and multiple sclerosis.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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