Thermo Fisher Scientific LGALS3 Monoclonal Antibody (OTI21C1), TrueMAB
LGALS3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 IHC(Paraffin)에 적합. 동결건조 형태로 제공되며, PBS 기반 버퍼에 8% 트레할로스 포함. 연구용으로 Galectin-3 관련 세포 이동 및 염증 반응 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI21C1 |
| Immunogen | Full-length human recombinant LGALS3 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Galactose-specific lectin that binds IgE. It may mediate, through the α3β1 integrin, CSPG4-induced endothelial cell migration.
Together with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis.
In the nucleus, it functions as a pre-mRNA splicing factor.
Involved in acute inflammatory responses, including neutrophil activation and adhesion, monocyte/macrophage chemoattraction, opsonization of apoptotic neutrophils, and mast cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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