Thermo Fisher Scientific L-Myc Polyclonal Antibody
Rabbit polyclonal antibody targeting human L-Myc. Validated for WB and IHC(P) applications. Recognizes multiple species with high predicted reactivity. Suitable for research use in studying c-Myc family proteins and tumorigenesis mechanisms.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from residues 105–154 of human L-Myc |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2266870 |
Product Specific Information
- Recommended positive control: human kidney
- Predicted reactivity: Cow (92%), Dog (92%), Guinea Pig (92%), Horse (92%), Mouse (100%), Rabbit (100%), Rat (100%)
Target Information
Cellular DNA-binding proteins encoded by the c-myc genes are involved in nucleic acid metabolism and mediate the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
L-Myc gene ontology annotations include:
- DNA binding function
- DNA-binding transcription factor activity, RNA polymerase II-specific
- Protein dimerization activity
- Regulation of inner ear auditory receptor cell differentiation
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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