Thermo Fisher Scientific Cdc42EP2 Polyclonal Antibody
Rabbit polyclonal antibody targeting Cdc42EP2 (BORG1), suitable for Western blot. Recognizes human Cdc42EP2 involved in actin cytoskeleton organization. Supplied as liquid, unconjugated, 1 mg/mL concentration. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human BORG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555674 |
Target Information
Cdc42, a small GTPase, regulates actin polymerization, elongation of cell shape, and cell signaling through interactions with various downstream effector proteins containing a Cdc42-binding motif known as a CRIB domain.
Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. It is highly expressed in heart and present at lower levels in liver and pancreas.
Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the actin cytoskeleton and may influence actin filament assembly and overall cell shape.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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