Thermo Fisher Scientific ERN2 Polyclonal Antibody
Thermo Fisher Scientific의 ERN2 Polyclonal Antibody는 인간 ERN2 단백질을 표적으로 하는 토끼 IgG 항체입니다. Western blot에 적합하며, 액상 형태로 제공됩니다. 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 39–72 amino acids from the N-terminal region of human ERN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion - Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2098730 |
Target Information
ERN2 serine/threonine kinase, also known as endoplasmic reticulum to nucleus signaling 2 protein, is a human homologue of the yeast Ire1 gene product. It plays a role in multiple aspects of the ER stress response in mammalian cells. Unlike closely related proteins, this pro-apoptotic factor appears to play no role in the unfolded-protein response. Overexpression of ERN2 activates both BiP and CHOP expression, leading to programmed cell death. Ern2 is suggested to be involved in several facets of the ER stress response in mammalian cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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