Thermo Fisher Scientific RCC1 Monoclonal Antibody (2F1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2F1

Immunogen

RCC1 (AAH07300, 312 a.a. approximately 421 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RCC1,uniProtId:P18754-1,ncbiNodeId:9606,antigenRange:312-421,antigenLength:421,antigenImageFileName:H00001104-M01_RCC1_P18754-1_House_mouse.svg,antigenImageFileNamePDP:H00001104-M01_RCC1_P18754-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: EGKAYSLGRA EYGRLGLGEG AEEKSIPTLI SRLPAVSSVA CGASVGYAVT KDGRVFAWGM GTNYQLGTGQ DEDAWSPVEM MGKQLENRVV LSVSSGGQHT VLLVKDKEQS

Target Information

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.