Thermo Fisher Scientific UBR2 Polyclonal Antibody
Thermo Fisher Scientific의 UBR2 Polyclonal Antibody는 인간 UBR2 단백질의 C-말단 펩타이드(aa 314-363)에 특이적으로 반응하는 토끼 다클론 항체입니다. Western blot에 최적화되어 있으며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human UBR2 (aa 314–363) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606828 |
Product Specific Information
- Peptide sequence: GLKLLSWLGS IIGYSDGLRR ILCQVGLQEG PDGENSSLVD RLMLSDSKLW
- Sequence homology:
- Cow: 100%
- Dog: 100%
- Guinea Pig: 100%
- Horse: 100%
- Human: 100%
- Mouse: 100%
- Rabbit: 93%
- Rat: 100%
- Zebrafish: 91%
Target Information
The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1, and Notch 1.
NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE, or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate.
Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1.
In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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