Thermo Fisher Scientific PDE4B Polyclonal Antibody
PDE4B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, ICC/IF, IP에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PDE4B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,500 |
| Immunocytochemistry (ICC/IF) | 1:300 |
| Immunoprecipitation (IP) | 1:350 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (C terminal) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.68 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris glycine, pH 7.4–7.9, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2299339 |
Product Specific Information
PA1-31135 detects PDE4B from rat, human, and mouse samples.
Target Information
The PDE4B gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family.
Cyclic nucleotides act as second messengers that regulate and mediate cellular responses to extracellular signals such as hormones, light, and neurotransmitters.
PDEs regulate the cellular concentrations of cyclic nucleotides and play a key role in signal transduction.
This gene encodes a protein that specifically hydrolyzes cAMP, and altered activity of this protein has been associated with schizophrenia and bipolar affective disorder.
Alternate transcriptional splice variants encoding different isoforms have been characterized.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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