Thermo Fisher Scientific GPR6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GPR6. Validated for IHC (paraffin) at 3 µg/mL. Recognizes conserved C-terminal peptide sequence. Supplied as liquid at 1 mg/mL, unconjugated. Store at 2–8°C short-term or −20°C long-term.
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Applications
Tested Applications and Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from C-terminus of human GPR6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long term storage, store at −20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2551114 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon: 100%
- Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Rabbit, Pig: 94%
- Elephant: 88%
- Opossum: 82%
Target Information
The G-protein-coupled receptor (GPCR) superfamily includes approximately 600–1,000 members and represents the largest known class of molecular targets with therapeutic relevance.
GPR6 is an orphan, constitutively active G-protein-coupled receptor involved in processes such as neurite growth, amyloid processing, and appetitive learning.
It is predominantly expressed in neurons of the striatum and is localized both on the cell surface and within intracellular compartments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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