Thermo Fisher Scientific EPC1 Polyclonal Antibody
EPC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간 EPC1(325–375 aa) 영역을 면역원으로 사용. 액상 형태로 4°C에서 보관, 1년 안정성 보장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 325 and 375 of human Enhancer of Polycomb 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex, which is involved in transcriptional activation of select genes primarily by acetylation of nucleosomal histones H4 and H2A.
This modification may alter nucleosome–DNA interactions and promote binding of modified histones with proteins that positively regulate transcription.
The NuA4 complex may be required for transcriptional programs associated with oncogene and tumor suppressor-mediated growth regulation, replicative senescence, apoptosis, and DNA repair.
It may also play a direct role in DNA repair when recruited to sites of damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: A303-110A-M_EPC1_Q9H2F5-1_Rabbit.svg)
(이미지: A303-110A-M_EPC1_Q9H2F5-1_Rabbit_PDP.jpeg)
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