Thermo Fisher Scientific COX8A Polyclonal Antibody
Human COX8A 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COX8A. Recombinant protein control fragment (Product # RP-101789) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640105 |
Product Specific Information
- Immunogen sequence: VPRAKIHSLP PEGKLGIMEL
- Highest antigen sequence identity to orthologs:
- Mouse: 45%
- Rat: 50%
Target Information
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some mitochondrial and some nuclear.
The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms.
COX8 exists as three isoforms:
- COX8a: liver and heart isoform
- COX8b: heart-specific isoform
- COX8c: expression pattern not fully elucidated
All three COX8 isoforms are components of the COX complex and play an important role in electron transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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