
Thermo Fisher Scientific SPTY2D1 Polyclonal Antibody
Rabbit polyclonal antibody against SPTY2D1 protein. Provides high specificity and sensitivity for histone chaperone research. Supplied in liquid form at 1 mg/mL concentration. Recommended storage at 4°C and shipped on wet ice. For research use only.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids between 75 and 125 of human SPTY2D1 (UniProt ID: Q68D10-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053).
Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053).
Binds DNA and histones and promotes nucleosome assembly in vitro (PubMed:23378026, PubMed:26109053).
Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053).
Modulates RNA polymerase I-mediated transcription.
Binds DNA with preference for branched DNA species such as Y-form DNA and Holliday junction DNA (PubMed:23378026).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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