Thermo Fisher Scientific Embigin Polyclonal Antibody
인간 Embigin 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. 세포막 단백질 연구 및 암세포 라인 분석에 유용.
- 카탈로그번호
- PA587887
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 33–260 of human EMB (NP_9408511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804481 |
Product Specific Information
Immunogen sequence:
DGSAPDSPFT SPPLREEIMA NNFSLESHNI SLTEHSSMPV EKNITLERPS NVNLTCQFTT SGDLNAVNVT WKKDGEQLEN NYLVSATGST LYTQYRFTII NSKQMGSYSC FFREEKEQRG TFNFKVPELH GKNKPLISYV GDSTVLTCKC QNCFPLNWTW YSSNGSVKVP VGVQMNKYVI NGTYANETKL KITQLLEEDG ESYWCRALFQ LGESEEHIEL VVLSYLVP
Positive Samples: Jurkat, MCF-7, THP-1
Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, synapse
Target Information
Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like V-type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis.
A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion.
Widely expressed in most tissues and embryonal carcinoma cells, as well as prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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