Thermo Fisher Scientific Embigin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_9408511) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Embigin,uniProtId:Q6PCB8-1,ncbiNodeId:9606,antigenRange:33-260,antigenLength:327,antigenImageFileName:PA5-87887_Embigin_Q6PCB8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87887_Embigin_Q6PCB8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.13 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804481

Product Specific Information

Immunogen sequence: DGSAPDSPFT SPPLREEIMA NNFSLESHNI SLTEHSSMPV EKNITLERPS NVNLTCQFTT SGDLNAVNVT WKKDGEQLEN NYLVSATGST LYTQYRFTII NSKQMGSYSC FFREEKEQRG TFNFKVPELH GKNKPLISYV GDSTVLTCKC QNCFPLNWTW YSSNGSVKVP VGVQMNKYVI NGTYANETKL KITQLLEEDG ESYWCRALFQ LGESEEHIEL VVLSYLVP; Positive Samples: Jurkat, MCF-7, THP-1; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, synapse

Target Information

Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis. A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion. Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.