Thermo Fisher Scientific TRIM22 Polyclonal Antibody
인간 TRIM22 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼(40% glycerol, 0.02% sodium azide) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRIM22. Recombinant protein control fragment (Product # RP-102255) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648915 |
Product Specific Information
Immunogen sequence:
NEVVKECQEK LQVALQRLIK EDQEAEKLED DIRQERTAWK NYIQIERQKI LKGFNEMRVI LDNEEQRELQ KLEEGEVNVL DNLAAATDQL VQQRQDASTL ISDLQRRLRG SSVEMLQDVI DVMKRSESWT LKKPKSVSKK LKSVFRV
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 54%
- Rat: 54%
Target Information
TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (a RING, a B-box type 1, and a B-box type 2) and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that its function may be to mediate interferon’s antiviral effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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