Thermo Fisher Scientific CENTD2/ARAP1 Polyclonal Antibody
Human ARAP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 고순도 항원 친화 크로마토그래피 정제. 4°C 보관, 연구용 전용.
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Thermo Fisher Scientific CENTD2/ARAP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1160 and 1210 of human centaurin, delta 2 (ankyrin repeat, and pleckstrin homology domains-containing protein 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeats.
This adaptor serves as a link between phosphoinositide-, Arf-, and Rho-mediated cell signaling.
ARAP1 supports plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is also involved in cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, promoting TRAIL-induced apoptosis in certain cell types.
Additionally, ARAP1 influences cell spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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