Thermo Fisher Scientific HOXD1 Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF)
  Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
REREGLLATAI PVAPLQLPLS GTTPTKFIKN PGSPSQSQEP S

Highest antigen sequence identity to the following orthologs:

• Mouse: 67%
• Rat: 71%

Target Information

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.
HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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