Thermo Fisher Scientific Calpain 13 Polyclonal Antibody
Human Calpain 13 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200–1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol) 내 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Calpain 13 (Product # RP-91752) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639244 |
Product Specific Information
Immunogen sequence:
DIDATQLQGL LNQELLTGPP GDMFSLDECR SLVALMELKV NGRLDQEEFA RLWKRLVHYQ HVFQKVQTSP GVLLSSDLWK AIENTDFLRG IF
- Highest antigen sequence identity to orthologs:
- Mouse: 79%
- Rat: 73%
Target Information
The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that act as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits and a common small regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive, and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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