Thermo Fisher Scientific Human AXIN1 Synthetic Peptide
Human AXIN1 단백질의 C-말단 14개 아미노산 서열 기반 합성 펩타이드. AXIN1 항체(PA5-21042)와 함께 차단 실험에 사용 가능. WNT 신호 경로 연구 및 암 관련 단백질 기능 분석에 적합. 연구용으로만 사용.
- 카탈로그번호
- PEP1156
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human AXIN1 Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human AXIN1.
PEP-1156 can be used as a blocking peptide with polyclonal antibody PA5-21042.
Target Information
AXIN1 is a cytoplasmic protein containing a regulation of G-protein signaling (RGS) domain and a disheveled and axin (DIX) domain. It functions as a negative regulator of the WNT signaling pathway that governs embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, and glycogen synthase kinase 3 beta to form a tetrameric complex regulating beta-catenin stabilization. Mutations in the AXIN1 gene are associated with various carcinomas, indicating its role as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.