Thermo Fisher Scientific NR5A1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NR5A1 (SF-1) N-terminus. Validated for Western blot and immunoprecipitation. Supports endocrine system development studies. Supplied as liquid, unconjugated, and stored at -20°C.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunoprecipitation (IP) | 0.1–0.5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human NR5A1 (UniProt ID: Q13285-1, antigen length: 461 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2902726 |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family. It contains two activation function domains (AF1 and AF2) required for interactions with nuclear receptors, coactivators, and corepressors such as SRC-1, GRIP1, CBP, and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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