Thermo Fisher Scientific USP34 Polyclonal Antibody
Thermo Fisher Scientific의 USP34 Polyclonal Antibody는 인간 단백질에 반응하는 토끼 유래 IgG 항체로, IHC 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, Wnt 신호 경로 조절 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 3350 and the C-terminus (residue 3395) of Human Ubiquitin Specific Protease 34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Turkey, Bovine, Dog, Horse, Guinea pig, Panda, Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of the Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to nuclear accumulation and positively regulating beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in processing of poly-ubiquitin precursors and ubiquitinated proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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