Thermo Fisher Scientific PHC3 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PHC3 (AAH22325, 1 a.a. approximately 151 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHC3,uniProtId:Q8NDX5-1,ncbiNodeId:9606,antigenRange:1-983,antigenLength:983,antigenImageFileName:H00080012-B01P_PHC3_Q8NDX5-1_House_mouse.svg,antigenImageFileNamePDP:H00080012-B01P_PHC3_Q8NDX5-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MAEAEFKDHS TAMDTEPNPG TSSVSTTTSS TTTTTITTSS SRMQQPQISV YSGSDRHAVQ VIQQALHRPP SSAAQYLQQM YAAQQQHLML HTAALQQQHL SSSQLQSLAA VQASLSSGRP STSPTGSVTQ QSSMSQTSVS SLNFFFLDLK F

Target Information

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.