Thermo Fisher Scientific ATP Citrate Lyase Polyclonal Antibody
ATP Citrate Lyase 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 Immunocytochemistry에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 고순도 항원 친화 정제 방식으로 제조되어 안정적인 신뢰성 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 430–480 of Human ATP-Citrate synthase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2803120 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues.
The enzyme is a tetramer (molecular weight ≈440,000) composed of identical subunits.
It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with the hydrolysis of ATP to ADP and phosphate.
Acetyl-CoA serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
In nervous tissue, ATP citrate lyase may be involved in the biosynthesis of acetylcholine.
Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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