Thermo Fisher Scientific TFEB Polyclonal Antibody
TFEB 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC(PFA)에서 사용 가능하며, 인간 및 생쥐 시료 반응성. 고순도 친화성 크로마토그래피 정제, 안정적인 PBS/글리세롤 저장용액 구성.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TFEB (Accession P19484), corresponding to amino acid residues M1–Q44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900667 |
Product Specific Information
Antibody detects endogenous levels of total TFEB.
Target Information
The Transcription Factor EB (TFEB) is a member of the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors.
Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1.
Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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