
Thermo Fisher Scientific UBAP2L Polyclonal Antibody
인간 UBAP2L 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며, 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBAP2L. Recombinant protein control fragment (Product #RP-94295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649171 |
Product Specific Information
Immunogen sequence:
PINPATAAAY PPAPFMHILT PHQQPHSQIL HHHLQQDGQL PYLQMILCCQ RQQEEQTGSG QRSQTSSIPQ K
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 79%
Target Information
NICE4, also known as UBAP2L (Ubiquitin-associated protein 2-like) or KIAA0144, is a 1,087 amino acid protein that is ubiquitously expressed. Phosphorylated upon DNA damage, NICE4 contains one UBA domain and is expressed as four isoforms produced by alternative splicing events.
The gene encoding NICE4 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and accounting for approximately 8% of the human genome. Chromosome 1 contains roughly 3,000 genes, many of which are associated with various diseases. Notable examples include the LMNA gene (linked to Hutchinson-Gilford progeria), MUTYH (familial adenomatous polyposis), and others associated with Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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