Thermo Fisher Scientific OGFOD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human OGFOD1. Recombinant protein control fragment (Product #RP-96780). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OGFOD1,uniProtId:Q8N543-1,ncbiNodeId:9606,antigenRange:398-538,antigenLength:542,antigenImageFileName:PA5-51863_OGFOD1_Q8N543-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51863_OGFOD1_Q8N543-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644964

Product Specific Information

Immunogen sequence: EPENNQMAIS NNSQQSNEQT DPEPEENETK KESSVPMCQG ELRHWKTGHY TLIHDHSKAE FALDLILYCG CEGWEPEYGG FTSYIAKGED EELLTVNPES NSLALVYRDR ETLKFVKHIN HRSLEQKKTF PNRTGFWDFS F

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 81%.

Target Information

OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.