Thermo Fisher Scientific IDH1 Monoclonal Antibody (OTI24A2), Biotin, TrueMAB
IDH1 (mutant R132H)에 특이적인 Biotin 결합 단일클론 항체로, ELISA에 적합합니다. Mouse IgG2b 형식이며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 친화 크로마토그래피 정제, 안정한 PBS/BSA/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:250–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI24A2 |
| Immunogen | Synthetic peptide around the R132 region of the human IDH1 conjugated to KLH |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Isocitrate dehydrogenases (IDH1) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes are divided into two subclasses: NAD(+)-dependent and NADP(+)-dependent.
Five isocitrate dehydrogenases have been identified:
- Three NAD(+)-dependent forms localized to the mitochondrial matrix
- Two NADP(+)-dependent forms, one mitochondrial and one cytosolic
The protein encoded by the IDH1 gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains a PTS-1 peroxisomal targeting signal and plays a role in regenerating NADPH for intraperoxisomal reductions and cytoplasmic NADPH production.
This antibody product is specific for IDH1 (mutant R132H).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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