Thermo Fisher Scientific p400 Polyclonal Antibody
Thermo Fisher Scientific의 p400 Polyclonal Antibody는 인간 유래 p400 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot 및 ICC/IF에 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관 권장.
- 카탈로그번호
- PA530780
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 136–430 of Human p400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548254 |
Product Specific Information
- Recommended positive control: MCF-7
- Predicted reactivity: Mouse (83%), Rat (82%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Component of the NuA4 histone acetyltransferase complex involved in transcriptional activation of select genes, principally through acetylation of nucleosomal histones H4 and H2A. This modification may alter nucleosome–DNA interactions and promote binding with proteins that positively regulate transcription. EP400 may be required for activation of E2F1 and MYC target genes during cell proliferation. The NuA4 complex ATPase and helicase activities are partly contributed by RUVBL1 and RUVBL2 association with EP400. May regulate ZNF42 transcription activity.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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