Thermo Fisher Scientific CD34 Polyclonal Antibody
CD34 단백질을 표적하는 Rabbit Polyclonal 항체로, Western Blot, IHC, ICC/IF에 적합합니다. 인간 및 제브라피쉬 반응성을 가지며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 줄기세포 표지 및 세포 부착 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human CD34 aa 336–385 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932640 |
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) expressed on many stem cell populations. It serves as a stem cell marker, with reversible expression in human hematopoietic stem cells. CD34 may function as a surface receptor involved in receptor-mediated endocytosis, regulating adhesion, differentiation, and proliferation of hematopoietic stem cells and progenitors. It may mediate attachment to the bone marrow extracellular matrix or stromal cells and act as a scaffold for glycan attachment, facilitating binding to lectins. The intracellular domain is phosphorylated by activated protein kinase C, suggesting a role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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