Thermo Fisher Scientific PSMD12 Polyclonal Antibody
Thermo Fisher Scientific의 PSMD12 폴리클로날 항체는 인간 PSMD12 단백질을 표적으로 하며, WB, IHC(P), ICC/IF 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 연구용으로 세포 증식 및 크로마틴 조절 관련 단백질 분석에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMD12. Recombinant protein control fragment (Product #RP-93548). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646069 |
Product Specific Information
Immunogen sequence:
WQQALKSVVL YVILAPFDNE QSDLVHRISG DKKLEEIPKY KDLLKLFTTM ELMRWSTLVE DYGMELRKGS LESPATDVFG STEEGEKRWK DLKNRVVEH
Sequence identity with orthologs:
- Mouse: 94%
- Rat: 95%
Target Information
This protein is a ubiquitously expressed nuclear protein belonging to a highly conserved subfamily of WD-repeat proteins. It binds directly to retinoblastoma protein, which regulates cell proliferation. It is found in histone deacetylase complexes, including the mSin3 co-repressor complex, and in protein complexes involved in chromatin assembly. The protein interacts with the BRCA1 tumor-suppressor gene and may play a role in the regulation of cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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