Thermo Fisher Scientific DPH5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DPH5. Recombinant protein control fragment (Product #RP-99786). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DPH5,uniProtId:Q9H2P9-1,ncbiNodeId:9606,antigenRange:189-284,antigenLength:285,antigenImageFileName:PA5-61242_DPH5_Q9H2P9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61242_DPH5_Q9H2P9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640767

Product Specific Information

Immunogen sequence: SVNQAAQQLL EIVQNQRIRG EEPAVTEETL CVGLARVGAD DQKIAAGTLR QMCTVDLGEP LHSLIITGGS IHPMEMEMLS LFSIPENSSE SQSING

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

Target Information

This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.