Thermo Fisher Scientific GPR83 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

14-28 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human GPR83. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR83,uniProtId:Q9NYM4-1,ncbiNodeId:9606,antigenRange:423,antigenLength:423,antigenImageFileName:PA5-33770_GPR83_Q9NYM4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-33770_GPR83_Q9NYM4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2551141

Product Specific Information

Percent identity with other species by BLAST analysis: Human (93%) Chimpanzee, Gorilla, Orangutan, Monkey, Mouse (87%) Gibbon, Galago, Marmoset, Rat, Bat, Hamster, Rabbit, Horse (80%).

Target Information

GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.