
Thermo Fisher Scientific Sintilimab Recombinant Human Monoclonal Antibody
종양 면역치료용 인간 항-PD-1 단일클론 항체로, ELISA 등 연구용에 적합함. IgG4 형식으로 CHO 세포에서 발현된 재조합 항체이며, 고순도 Protein A 정제 제품. 냉동(-20°C) 보관 권장, 반복 동결·해동 피할 것.
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Applications
- ELISA
Tested Dilution
- 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG4, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human PDCD1 / PD1 / CD279 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.57 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911363 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Sintilimab is a fully human anti-PD-1 antibody for tumor immunotherapy. It adopts an IgG4 molecular framework and includes a modified hinge region sequence (S228P). As a PD-1 pathway blocker, Sintilimab binds to PD-1 molecules on T cells and relieves inhibitory effects on T-cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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