Thermo Fisher Scientific CGB2 Monoclonal Antibody (4F8)
CGB2 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal antibody (Clone 4F8). Western blot 및 ELISA에 적합하며, Human 시료 반응성. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F8 |
| Immunogen | CGB2 (NP_203696, 1 a.a. ~ 56 a.a.) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSTSPVLAED IPLRERHVKG AAAVAAAEHG RDMGIQGAAS ATVPPHQCHP GCGEGG
Target Information
The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes arranged in tandem and inverted pairs on chromosome 19q13.3, contiguous with the luteinizing hormone beta (LHB) subunit gene.
The CGB genes are primarily distinguished by differences in the 5′ untranslated region.
This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of the CGB subunit; however, detection of CGB1 and CGB2 transcripts in vivo and their presence on polysomes suggested that these transcripts are translated.
To date, a protein product corresponding to CGB2 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share similarity with functional CGB subunits (PMID:8954017).
However, a 163 aa protein translated from a different frame is about the same size and shares 98% identity with other CGB subunits.
[Provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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