Thermo Fisher Scientific CGB2 Monoclonal Antibody (4F8)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSTSPVLAED IPLRERHVKG AAAVAAAEHG RDMGIQGAAS ATVPPHQCHP GCGEGG

Target Information

The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes arranged in tandem and inverted pairs on chromosome 19q13.3, contiguous with the luteinizing hormone beta (LHB) subunit gene.
The CGB genes are primarily distinguished by differences in the 5′ untranslated region.
This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of the CGB subunit; however, detection of CGB1 and CGB2 transcripts in vivo and their presence on polysomes suggested that these transcripts are translated.
To date, a protein product corresponding to CGB2 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share similarity with functional CGB subunits (PMID:8954017).
However, a 163 aa protein translated from a different frame is about the same size and shares 98% identity with other CGB subunits.
[Provided by RefSeq, Jul 2008]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.