Thermo Fisher Scientific p400 Polyclonal Antibody
인간, 마우스, 랫트 반응성의 p400 단백질을 표적으로 하는 Rabbit Polyclonal Antibody. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human p400, amino acids 1051–1250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of the NuA4 histone acetyltransferase complex involved in transcriptional activation of select genes by acetylation of nucleosomal histones H4 and H2A. This modification may alter nucleosome–DNA interactions and promote interaction with proteins that positively regulate transcription. May be required for activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities are partly contributed by RUVBL1 and RUVBL2 association with EP400. May regulate ZNF42 transcription activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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