Thermo Fisher Scientific TAAR1 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1.3 µg/mL

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gibbon, Monkey, Marmoset, Tamarin (100%)
Orangutan, Cat, Horse (88%)
Bovine, Elephant, Panda, Rabbit, Pig (81%)

Target Information

TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach.
An EST for TA1 has been identified from a human stomach cancer library.

G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules, with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
An array of activating ligands participate in the conformation of GPCRs, leading to signaling via G-proteins and downstream effectors. Studies have also shown the mechanisms of negative regulation of GPCRs, which have significant implications for cellular physiological actions and pharmacological research for new drug candidates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.