Thermo Fisher Scientific CD10 Monoclonal Antibody (56C6)
CD10 단백질을 표적하는 Mouse IgG1 단일클론 항체로, WB, IHC(P), FACS 등 다양한 응용에 사용 가능. 인간 및 랫트 시료 반응성이 우수하며, 4°C에서 안정적으로 보관. 진단용이 아닌 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:20–1:200 | View 5 publications |
| Immunohistochemistry (IHC) | – | View 50 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:30–1:60 | View 3 publications |
| Immunocytochemistry (ICC/IF) | – | View 2 publications |
| Flow Cytometry (Flow) | 1:2 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 56C6 |
| Immunogen | Recombinant external domain of CD10 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Tissue culture supernatant |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10983979 |
Product Specific Information
MA5-14050 targets CD10 in WB, IF, FACS, and IHC(P) applications and shows reactivity with Human and Rat samples.
This antibody is not recommended for LNCAP cells in Western blot applications.
The immunogen is the recombinant external domain of CD10 protein.
Target Information
CD10 (Common Acute Lymphocytic Leukemia Antigen, CALLA) is a cell surface enzyme with neutral metalloendopeptidase activity that inactivates various biologically active peptides.
It is expressed on lymphoblastic, Burkitt’s, and follicular germinal center lymphoma cells, immature B cells in adult bone marrow, and cells from patients with chronic myelocytic leukemia (CML).
CD10 is also found on breast myoepithelial cells, bile canaliculi, fibroblasts, and highly expressed on kidney and gut epithelial brush borders.
It is a 100 kDa type II transmembrane glycoprotein encoded by a single gene (>45 kb) with alternatively spliced 5′ untranslated regions producing four mRNA transcripts.
Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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