
Thermo Fisher Scientific 8-oxo-dG Phosphoramidite, standard grade, serum vial bottle
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Thermo Scientific™
8-oxo-dG Phosphoramidite, standard grade, serum vial bottle
8-oxo-dG CEP is a phosphoramidite containing an oxidized deoxyguanosine (dG), and it facilitates the investigation of the structure and activity자세히 알아보기
8-oxo-dG CEP is a phosphoramidite containing an oxidized deoxyguanosine (dG), and it facilitates the investigation of the structure and activity when incorporated into an oligonucleotide. In nature, 8-oxo-dG DNA lesions are formed with reactive oxygen species (ROS), and is removed by by the base excision repair (BER) mechanism. This modification is significant in mutagenesis, carcinogenesis, and has been proven useful as a biomarker. This product is supplied in a 5 mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers of oligonucleotide synthesizers.
Features:
• Full chemical name—5-O-(4,4
-Dimethoxytrityl)‐N2-isobutyryl-8-oxo-deoxyguanosine-3`-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H54N7O9P
• Base—8-oxo-dG
• Base Protection—iBu
• Formula weight—855.9 g/mol
• CAS number—143060-53-1
• HPLC Purity—≥98.0%
• 31P NMR Purity—≥98.0%
사양
용도(장비)AKTA Synthesizers, Applied Biosystems Synthesizers
제품 유형8-oxo-dG CEP
뉴클레오시드 유형Deoxyguanosine (dG)
배송 조건Room Temperature
순도98%
수량0.25 g
시약 유형Phosphoramidite
등급Standard
핵산 유형DNA
형태Powder
Unit SizeEach
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